Last updated: March 12,
2024
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Web Designer: Dr. Ankur Sharma
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DEPARTMENT OF VETERINARY MEDICINE Dr G.C. Negi COVAS, CSK HPKV – Palampur-176062 (H.P.)
MAJOR RESEARCH ACHIEVEMENTS 1. Studies on chronic bovine haematuria in cattle: The problem of chronic bovine haematuria is prevalent in some pockets of Mandi, Kullu, Shimla and Kinnaur district of Himachal Pradesh. The affected animal showed symptoms of weakness and blood in urine due to neoplastic growth in bladder. There is no permanent cure. However symptomatic treatment either mineral mixture and haematinic mixture can increase the productivity of animals.
2. Studies on Respiratory Distress Syndrome in Equines: The study indicated that RDS in quite prevalent among horses, ponies and mules in Kangra and Manali districts. Affected horses showed Polypnoea, tachycardia and prominent abdominal respiration, coughing and nasal discharge. Ciprofloxacin proved most effective in clinical cases followed by gentamicin when used along with supportive and symptomatic therapy.
3. Therapeutic Efficacy of Pahari Pudina in indigestion in cattle: Incidence of simple indigestion and acidic indigesion among bovine is high. The study indicated that the local herb namely Pahari pudine (Mentha spicata) is effective in these conditions as well as economically viable therapy for the farmers.
4. Studies on Haemocrisis in Cattle of Palam Valley of H.P.: Anemia (haemocrisis) has been recognized as a problem of concern. Overall incidence of anaemia was recorded to be 60.8%. Further, in 55.2% cases, anaemia was due to mineral deficiency, 11.1 % due to haemoprotozoan diseases and 7.8 % due to helminthiasis. Blood transfusion proved a valuable therapeutic tool in critically anaemic animals.
5. Studies on gastro-intestinal helminthiasis in cattle: An overall incidence of 33.66 % was observed for gastro intestinal helminthes in the Palam Valley. Amphistomes, Fasciola, strongyles, Trichuris, Toxocara and Moneizia spp were detected. Amphistomiasis was most prevalent (21.66%). Oxyclozanide was more effective against amphistomes than triclabendazole and fenbendazole was effective against stongylosis.
6. Pattern of parasitism in equines: Based on the study, overall prevalence of gasto intestinal helminthiasis was 87.6 %. Strongyle infection dominated the other infections like parascaris, oxyuris and the gastrodiscus. Fenbendazole proved more effective than closantel against the helminthes particularly strongyles in equines.
7. Diagnostic & Therapeutic studies on Mastitis: Overall incidence of mastitis was found to be 13.59%. Higher incidence was reported in crossbreds, high yielders in early stage of lactation. CMT was found sensitive, simple and dependable test for field diagnosis of mastitis. Clinically, combination of ampicillin and cloxacillin along with I/M vitamin E was more efficacious in management of mastitis.
8. Studies on Lantana Toxicity in Bovines: Study indicated that lantana ingested animal showed clinical signs like anorexia, constipated faeces, decreased urination, dry muzzle and swelling of eye lids and base of pinna. Combined therapy comprising activated charcoal, dextrose saline, liver extract, purgative and rumenotorics gave encouraging results especially in early presented case.
9. Studies on pattern of canine endoparasitism: Overall incidence of helminthiasis in canine of Palam Valley was 27.70 %. Dipylidium spp was most prevalent (11.11%) whereas Spirometra, Ancylostoma and Toxocara spp each accounted for 5.55%.The recovery rate was 100 % in all the parasitised dogs with triworm against Dipylidium and Spirometra and Albendazole & Fenbendazole against Toxocariasis and Ancylosomiasis.
10. Investigations on anaemia in dogs: The overall incidence of anaemia was recorded as38 % in Palampur area. In majority of the cases (60 %), anaemia was of microcytic hypochromic type. Helminthic infections, mineral deficiencies, liver dysfunction, parasitic infections, digestive disturbances alone or in combination were found to be the cause of anaemia. Blood transfusion proved a valuable therapeutic tool in critically anaemic dogs.
11. Investigations on haemoglobinuria in cattle: Study revealed that 88.63% cases of haemoglobinurea were of blood protista infection either as single infection (Babesia bigemina) or mixed infection (Babesia with Anaplasma or Theileria) and 11.37 % cases were of nutritional haemoglobinuria. Combined treatment comprising Berenil and Oxytetracycline LA with supportive therapy gave encouraging results in blood protista infection. In nutritional haemoglobinuria, combined treatment comprising inj. Sodium acid phosphate (20%) @ 20 gm/100kg wt., inj.Tonophosphan, oral sodium acid phosphate with supportive therapy was effective.
12. Studies on bovine mastitis in Kangra Valley of Himachal Pradesh: The overall incidence of the disease was observed to be 12.83%. Highest incidence was observed in crossbred (75.00%) and it was in the 4th parity (38.33%). Staphylococcus spp. (58.06%) was the major isolate followed by Streptococcus spp. (19.36%), E.coli (12.90%), Bacillus spp. (5.38%) and Pseudomonas spp. (4.30%). Clinically, intramammary administration of cefoperazone alongwith parenteral administration of Vit. E & Se was most effective in mastitis.
13. Clinico- therapeutic studies on enteritis in neonatal calves: The overall incidence of neonatal calf diarrhoea was found to be 47.97% . Out of 64 diarrhoeic faecal samples cultured, 56 (87.50%) were positive for Escherichia coli, 2 (3.12%) for Proteus sp. and 6 (9.37%) for mixed infection. Of these 64 samples, 16 (25%) were also positive for Cryptosporidium sp. Treatment with interavenous fluid (RL) along with parenteral enrofloxacin was better than parenteral gentamicin. Calves affected with Cryptosporidium sp. along with the bacterial infection treated with ofloxacin along with nitazoxanide showed better improvement as compared to nitazoxanide alone.
14. Investigations on canine mange: The study revealed that prevalence of mange was 15.71 %. Face, periorbital area and fore legs were found to be the site of predilection for demodectic mites while as ventral surface of tail and ears were the predilection sites for sarcoptic mites. Injectable and Topical preparations of Ivermectin were most and equally effective in curing both demodectic and sarcoptic mange followed by oral Ivermectin while Amitraz was found to be least effective.
15. Investigations on hepatic dysfunctions in canine: The dogs suffering from liver dysfunctions showed symptoms like inappetance/anorexia, ascites, vomition, dullness, constipation, fever, diarrhoea, pale mucosa, jaundice, weight loss, melaena and weakness. The mean activities of aspartate aminotransferase, alanine aminotransferase and alkaline phosphatse were markedly higher in all the hepatic dysfunctions. Biochemical examination revealed hypoproteinaemia and hypoalbuminaemia in primary hepatic dysfunctions. Ultrasonographic studies were found very helpful in evaluation of liver status and classification of hepatopathies. Following the combined therapy comprising hepatoprotectant (Silymarin), fluid therapy, liver extract, antibiotic, antiemetic and diuretics, 60 per cent cases of hepatitis and 40 percent cases of cirrhosis could be treated successfully.
16. Clinico-therapeutic studies on Bovine Cutaneous Papillomatosis: Studies on Bovine cutaneous papillomatosis revealed prevalence of warts in 6.16% of dairy cattle. The incidence was higher in cross bred animals and Jersey cross was maximum affected (74.22%). Teats papillomatosis was recorded in 93.81 per cent cases. Warts on other body parts were present in 17.53 per cent cases. Combined use of anthiomaline along with levamisole was more efficacious (60 %) than anthiomaline alone (54.54%). Autogenous wart vaccine was effective in 71.42 per cent cases. Levamisole and ivermectin were effective in early and mild cases only and were effective in 27.27 and 36.36 per cent cases respectively. Based on the present study, it is advocated to use combination of anthiomaline and levamisole or autogenous vaccine for treatment of papillomatosis in cattle.
17. Investigations on gastroenteritis in dogs : Investigation was conducted on 63 dogs suffering from gastroenteriris and enteritis. From 45 cases of gastroenteritis, 18 cases were detected positive for canine parvovirus infection. Most of the dogs suffering from gastroenteritis and enteritis were dehydrated and all the dogs were dehydrated in CPV gastroenteritis. Blood biochemical study revealed hypoglycaemia, hypoproteinemia, hypoalbuminemia, hypokalemia, hypochloremia and increase in BUN in all the groups. The activity of CK-MB was markedly elevated in canine parvoviral gastroenteritis group. Combination of levofloxacin along with fluid and supportive therapy proved most effective in the treatment of gastroenteritis and CPV gastroenteritis. Similarly, levofloxacin also proved better as compared to ofloxacin in treating canine enteritis.
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